Clinical Trial for Rheumatoid arthritis

Rheumatoid arthritis is an uncommon form of arthritis. Rheumatoid Arthritis is an autoimmune disease that occurs when your immune system attacks the lining of your joints. This causes joint pain, stiffness, swelling, and redness that can move to any joint, at any time. You may also have other symptoms like feeling tired or having a fever. Better treatment options are needed for people who suffer with Rheumatoid Arthritis. Right now, local doctors are looking for people who have Rheumatoid Arthritis to participate in local research studies. Click the link below to learn more:





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What are clinical trials?

Every day  I read a bit more about clinical trials and how they can improve lives. Well, THEY CAN! People like to help and are excited about the fact that they might be part of something that is can make a difference in peoples lives. People don’t like the feeling of powerlessness that they feel when they can’t change things, make things better. They feel strongly that if if doctors can’t make patients feel better, they might be able to. They don’t feel quite as powerless if they join a clinical trial which might help doctors shed light on what makes patients sick. There are many clinical trials in which patients participate and take advantage of, too. It is under this section head that I will be posting studies that may interest you and may be in your areas. Most reimburse for your time and travel.

What are clinical trials?

Clinical trials are research studies, designed to answer specific health questions about a particular illness. Carefully conducted clinical trials are the fastest way and the safest way to find ing moreaeffective treatments for diseases.

There are also interventional trials which determine whether experimental treatments or new ways of using old treatments are safe and effective. Observational trials address health issues in large groups of people or populations in natural settings.

Different types of clinical trials? There’s more than one?

  •  treatment trials are as described. They test new treatments, new combinations of drugs, or new approaches to surgery or possibly radiation therapy. This is what most people think of when hearing the term
  •  Prevention clinical trials look for better ways to ‘prevent’ a certain disease:
    • in people who have never had the disease
    • to prevent a disease from returnin
    • These approaches may include medicines, vitamins, vaccines, minerals, or lifestyle changes
  •   Diagnostic clinical trials are conducted to find better tests or procedures for diagnosing a particular disease or condition.
  •   Screening clinical trials test the best way to detect certain diseases or health conditions.
  •   Quality of Life clinical trials (or Supportive Care trials) explore ways to improve comfort and the quality to life if the disease is too far advanced to benefit from curative clinical trials, but the course can be altered by palliative efforts.
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About clinical trials

I learned a bit more about clinical trials this week: Until now, I thought that in clinical trials, some patients were offered an experimental med that could help them while other  patients got a placebo, or ‘sugar pill.’ That’s it, the old either/OR! Some patients get the study drug that has the potential to save them, other’s don’t. That is it, end of story:

NOT. This week, I found out that in most studies, you still get the treatment you’ve been getting all along. But, in clinical trials some patients are given the trial med IN ADDITION to their regular med/s. Others receive a placebo IN ADDITION to their regular med/s. Now, when I enter a clinical trial if I’m accepted, I sure as heck hope I am given the ‘real deal’ but if not, there are other reasons!

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What is Pulmonary Hypertension?

We’ve talked about some ways in which lupus can affect the heart: its inflammation can cause pericarditis; a painful inflammation of the lining around the heart, lupus patients are at an increased risk for development of Coronary Artery Disease, dyslipidema and many other heart-related problems.

Pulmonary Hypertension is not to be confused with high blood pressure, the systemic type in which your doctor measures your blood pressure with a cuff around your arm. For the purposes of this discussion, we speak of PULMONARY hypertension, or HIGH BLOOD PRESSURE IN THE LUNGS and treatment for it involves sophisticated treatment by subspecialists- after a through diagnostic workup. The World Health Organization has chosen to classify 5 types of Pulmonary Hypertension into Groups:

Group 1. Pulmonary Arterial Hypertension-the Pulmonary Artery becomes narrowed, so the pressure inside this artery becomes high.

Group 2. Pulmonary Hypertension due to left heart disease. This is often seen when stiff LEFT-SIDED HEART vessels don’t completely relax. A good example might be one which is caused by left ventricular diastolic dysfunction.

Group 3. Pulmonary Hypertension due to lung disease- the diseases here include COPD, mainly empyhsema and chronic bronchitis, as well as any disease that leads to scarring of the lungs, like pulmonary fibrosis and sleep-disordered breathing. In this instance (sleep-disordered breathing) CPAP for Obstructive Sleep Apnea is necessary.

Group 4. Pulmonary Hypertension due to blood clots in the lungs: this is sometimes called Chronic Thromboembolic Pulmonary Hypertension and in it, (blood clots) form within the lungs causing pulmonary hypertension by blocking the flow of blood through the pulmonary arteries., not only raising the blood pressure in the pulmonary artery, but since blood flow is blocked, more clots form.

Group 5. blood and other rare disorders that result in Pulmonary Hypertension-or Chronic Thromboembolic Pulmonary Hypertension. For an unknown reason, blood clots form in the lungs and in addidtion to the formation of clots which create more clots, these clots increase the pressure inside the pulmonary arteries.

The diagnosis of Pulmonary Hyptertension is often one made during a work-up of shortness of breath. Shortness of breath can have multiple causes and unless diagnosed and treated by subspecialists early, the shortness of breath of Pulmonary Hypertension  can have a poor outcome.

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